Archives: Research Papers

Telemedicine applications for cancer rehabilitation: a scoping review

BACKGROUND: Cancer is a significant public health issue worldwide. Treatments such as surgery, chemotherapy, and radiation therapy often cause psychological and physiological side effects, affecting patients’ ability to function and their quality of life. Physical activity is crucial to cancer rehabilitation, improving physical function and quality of life and reducing cancer-related fatigue. However, many patients face barriers to accessing cancer …

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Integrating molecular biomarkers in breast cancer rehabilitation. What is the current evidence? A systematic review of randomized controlled trials

BACKGROUND: Quality of life issues is a crucial burden in breast cancer (BC) survivors with relevant implications in terms of survivorship and health-care costs. The increasing long-term survival of these patients provides new challenges, with translational research now focusing on innovative and tailored approaches to improve their complex management. In this scenario, several emerging biomarkers have the potential to improve …

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Obesity and cancer rehabilitation for functional recovery and quality of life in breast cancer survivors: a comprehensive review [with consumer summary]

Obesity is a global health challenge with increasing prevalence, and its intricate relationship with cancer has become a critical concern in cancer care. As a result, understanding the multifactorial connections between obesity and breast cancer is imperative for risk stratification, tailored screening, and rehabilitation treatment planning to address long-term survivorship issues. The review follows the SANRA quality criteria and includes …

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Does resistance training ameliorate cancer-related fatigue in cancer survivors? A systematic review with meta-analysis [with consumer summary]

PURPOSE: Cancer-related fatigue (CRF) is unrelenting. As neither rest nor sleep ameliorates cognitive, emotional, and physical symptoms, quality of life is diminished. This study examines resistance training (RT) effectiveness on CRF in cancer survivors. The secondary aims were to identify the dose-response relationship of RT frequency, intensity, and volume on CRF in different cancer survivor populations. MATERIALS AND METHODS: Systematic …

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Exercise-based interventions for postoperative rehabilitation in breast cancer patients: a systematic review and meta-analysis of randomized controlled trials

BACKGROUND: This systematic review and meta-analysis aim to evaluate the effects of exercise interventions on pain, lymphoedema, shoulder joint range of motion (ROM), muscle strength, and quality of life in postoperative breast cancer patients, and to provide evidence-based recommendations for clinical practice. METHODS: This systematic review and meta-analysis adhered to PRISMA guidelines and was registered on PROSPERO (CRD420251045309). A thorough …

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The role of virtual reality in breast cancer survivors: a scoping review [with consumer summary]

OBJECTIVE: This scoping review aims to analyze features, functions, and effectiveness evaluation of VR in the application of breast cancer care. METHODS: A scoping review was conducted based on the framework suggested by Arksey and O’Malley. Eight electronic databases (ie, PubMed, EMBASE, Cochrane Library, Web of Science, CINAHL, CNKI, China Wanfang Database, and China Biology Medicine disc.) was searched. Articles …

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Effectiveness of exercise-based interventions in preventing cancer therapy-related cardiac dysfunction in patients with breast cancer: a systematic review and network meta-analysis [with consumer summary]

BACKGROUND: Despite advances in cancer treatment that have improved survival rates among patients with breast cancer, they are at high risk of developing cancer therapy-related cardiac dysfunction, which typically manifests as heart failure. Although exercise improves cardiorespiratory fitness in these patients, its effectiveness in preventing cancer therapy-related cardiac dysfunction remains unclear. OBJECTIVE: To assess the effectiveness of exercise-based interventions using …

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2017 comprehensive update of the Canadian Cardiovascular Society guidelines for the management of heart failure (updated from 2006)

Since the inception of the Canadian Cardiovascular Society heart failure (HF) guidelines in 2006, much has changed in the care for patients with HF. Over the past decade, the HF Guidelines Committee has published regular updates. However, because of the major changes that have occurred, the Guidelines Committee believes that a comprehensive reassessment of the HF management recommendations is presently …

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