Dynamic task-based rehabilitation and time to loss of toilet ambulation in a palliative care unit: a retrospective cohort study.

PURPOSE: To determine whether dynamic-task rehabilitation, compared with bedside-only or no rehabilitation, is associated with longer time to loss of toilet ambulation among patients with advanced cancer in a palliative care unit (PCU). METHODS: This retrospective study included patients with cancer admitted to a PCU who died during hospitalization (January 2020-March 2024). Eligible patients had walked to an in-room fixed …

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Exploring optimal group dynamics and their feasibility during a live-remote exercise program for cancer survivors: an international concept mapping study.

PURPOSE: Live-remote supervised exercise helps cancer survivors reduce the negative side effects of their treatment, and group dynamics are an integral aspect of successful rehabilitation outcomes. In this international group concept mapping study, we investigated which aspects of peer interaction and trainer behaviour participants consider important and how feasible those preferences are according to exercise professionals. METHODS: Participants who completed …

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Psycho-Social Rehabilitation After Curative Breast Cancer Treatment: A Review.

INTRODUCTION: With advances in early detection and multimodal therapy, survival after breast cancer has significantly improved. However, completion of curative treatment is not necessarily the end of patient suffering. Survivors frequently experience persistent psychological distress, social role disruption, altered body image, sexual dysfunction, fear of recurrence (FCR), and occupational challenges. Psycho-social rehabilitation is therefore a critical component of survivorship care. …

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Exercise-induced metabolic reprogramming in lung cancer and its translational implications for therapeutic advancement.

Lung cancer remains one of the leading causes of cancer-related mortality worldwide, characterized by profound metabolic reprogramming that sustains malignant growth, immune evasion, and therapeutic resistance. Aberrant activation of glycolysis, increased fatty acid synthesis and uptake, and dysregulated glutamine metabolism provide energy and biosynthetic substrates while reshaping the tumor microenvironment through lactate accumulation, acidosis, and angiogenic signaling. Experimental and clinical …

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Narrative review of non-pharmacological interventions for chemotherapy-induced peripheral neuropathy: exercise, physical therapy, cryotherapy and acupuncture.

PURPOSE: Chemotherapy-induced peripheral neuropathy (CIPN) is a heterogeneous, treatment-limiting adverse event of cytotoxic chemotherapy that impairs sensory, motor, autonomic and balance function, and substantially reduces cancer patients’ quality of life. Current pharmacotherapy options are limited: duloxetine is the only guideline-recommended agent for established painful CIPN, while no drugs are approved for primary prevention. Non-pharmacological interventions have emerged as promising adjunctive …

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Optimal Exercise Dose for Improving Multidimensional Health Outcomes in Colorectal Cancer Patients: A Systematic Review, Meta-Analysis and Meta-Regression.

This study aimed to investigate the dose-response relationships between exercise prescription parameters and a range of health outcomes in patients with colorectal cancer (CRC). The following PRISMA guidelines, a systematic search of five databases was conducted. The inclusion criteria were randomized controlled trials (RCTs) of exercise interventions lasting ≥ 4 weeks in patients with CRC. Robust Variance Estimation (RVE) was used to …

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Associations of Cancer Rehabilitation During Hospitalization for Cancer Treatment With Survival and Post-Discharge Healthcare Utilization: A Multicenter Retrospective Cohort Study.

BACKGROUND: Rehabilitation is increasingly recognized as an essential component of oncology care, but there remains limited evidence regarding its broader impact on patient outcomes. This study examined the associations of inpatient cancer rehabilitation with survival and post-discharge healthcare utilization among patients with diverse cancer types. METHODS: We conducted a multicenter retrospective cohort study using cancer registry-linked claims data from designated …

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Development of CaReScreen, a Digital Health Tool for Assessing Late Effects and Cancer Rehabilitation Needs in Cancer Survivors: Protocol for a Qualitative Development and Formative Design Study.

BACKGROUND: Due to advances in cancer diagnostics and treatments, life expectancy after cancer and the number of cancer survivors are increasing. Symptoms and late effects frequently occur in cancer survivors, with a negative impact on functioning and participation in society. Digital health tools might be helpful to systematically assess symptom burden of late effects and rehabilitation needs. OBJECTIVE: This paper …

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Three-dimensional evaluation and optimization of breast cancer rehabilitation science popularization videos on mainstream video platforms: a cross-sectional study in Mainland China.

BACKGROUND: With the growing number of breast cancer survivors, rehabilitation has become a critical component of comprehensive cancer care. Mainstream video platforms have emerged as a primary channel for patients to access rehabilitation information, yet the quality of such content remains unevaluated. This study aimed to systematically assess the quality and dissemination characteristics of breast cancer rehabilitation-related videos on TikTok, …

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Measurement and Reporting of Oxidative Stress and Antioxidant Biomarkers in Exercise Intervention Studies in Adults with Cancer: A Scoping Review.

Oxidative stress has been implicated in both cancer pathogenesis and treatment-related toxicity, and structured exercise has been proposed as a non-pharmacological strategy that may help modulate this redox imbalance in patients and survivors with cancer, although the consistency of this effect across the existing literature remains unclear. This scoping review, conducted in accordance with PRISMA-ScR guidance, searched four databases for …

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