Archives: Research Papers

Identification of high-impact chronic pain among cancer survivors: a cross-sectional study using the Graded Chronic Pain Scale framework.

PURPOSE: Chronic cancer-related pain is a prevalent and often under-recognized issue among individuals living with or after cancer. Clinically useful tools are needed to classify pain severity and impact and to identify those requiring targeted support. This study applied the Graded Chronic Pain Scale-Revised (GCPS-R) in a cohort of cancer survivors and examined differences in pain characteristics and psychosocial factors …

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Psychological Readiness for Surgery Through Prehabilitation and Treatment: A Longitudinal Qualitative Study.

BACKGROUND: Psychological prehabilitation aims to prepare patients for cancer treatment, yet psychological readiness is under-specified and distress during and after treatment is common. A patient-informed account of readiness is needed to guide readiness-focused, proactive psychological support in cancer care. AIMS: To examine patients’ experiences of psychological readiness for cancer surgery across the prehabilitation-treatment pathway. METHODS: We used a longitudinal qualitative …

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Evaluation of the Clinical Functioning Information Tool (ClinFIT) in Colorectal Surgical Prehabilitation: A Prospective Observational Study.

OBJECTIVE: To evaluate the construct validity and clinical associations of the Clinical Functioning Information Tool (ClinFIT) with routinely collected preoperative risk and functional capacity measures in a colorectal cancer prehabilitation cohort. DESIGN: Prospective observational study of routinely collected prehabilitation clinic data. METHODS: Adults with colorectal cancer at a tertiary cancer centre were assessed in the prehabilitation clinic using validated tools …

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Feasibility, uptake, and exploratory outcomes of an individualized exercise program in pediatric oncology: a prospective single-center pilot study.

INTRODUCTION: Exercise interventions may help mitigate treatment-related physical impairment in pediatric oncology, but implementation in routine care remains challenging, particularly during active treatment and in heterogeneous patient cohorts. PATIENTS: This prospective single-center pilot study evaluated an individualized exercise program for children and adolescents aged 4-17 years undergoing cancer treatment during the COVID-19 pandemic. METHOD: The program combined supervised in-hospital exercise, …

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Risk-Adaptive Cardio-Oncology Rehabilitation: A Narrative Review of Exercise Prescription, Multimodal Monitoring, and Implementation Pathways.

: Cardiovascular toxicity and pre-existing cardiovascular disease can affect cancer-treatment tolerance, functional recovery, and survivorship. This narrative review aimed to summarize current evidence and propose an author-derived risk-adaptive clinical framework for adult cardio-oncology rehabilitation (CORE), organized around exercise prescription, multimodal monitoring, and implementation. : PubMed/MEDLINE and the Web of Science Core Collection were searched from database inception through 27 July …

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Factors Associated with Meeting Physical Activity Guideline Recommendations in a Single Community Rehabilitation Center in Singapore: An Exploratory Study.

Physical exercise is a vital component of cancer rehabilitation, with demonstrated improvements in cancer health-related outcomes, relapse rates, mortality and overall survival, yet global participation remains low. In Singapore, uptake of community cancer rehabilitation is limited despite high prevalence of treatment-related impairments. A cross-sectional study was conducted among adults (≥21 years) enrolled in the Singapore Cancer Society Rehabilitation Center between …

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Health-related quality of life by human immunodeficiency virus status in a cross-sectional survey of gay and bisexual prostate cancer survivors.

OBJECTIVE: Prostate cancer is the most common invasive cancer in gay and bisexual men (GBM). Despite the unique sexual and urinary concerns of this group, studies of prostate cancer rehabilitation have primarily focused on heterosexual men. GBM also have high prevalence of human immunodeficiency virus (HIV), which may be associated with lower health-related quality of life (HRQOL). We examined the …

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‘You’ve Given Me My Voice’-Enhancing Engagement in Exercise Oncology Research: A Patient and Public Involvement Approach to Co‑Designing a Pre‑Radiotherapy Exercise Programme With People Living With Lung Cancer.

BACKGROUND: Emerging evidence suggests exercise may improve radiotherapy efficacy by reducing treatment resistance caused by tumour hypoxia. However, recruitment to exercise oncology studies is low (median 38%), particularly for people with lung cancer. One strategy to address such engagement barriers is by collaborating through Patient and Public Involvement and Engagement (PPIE). OBJECTIVE: To co-design an acceptable pre‑radiotherapy exercise programme for …

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Feasibility of the Golf Recreational Exercise for Enhanced Survivorship in prostate cancer survivors undergoing hormone therapy.

BACKGROUND: Prostate cancer (PCa) survivors undergoing androgen deprivation therapy (ADT) experience significant physical and psychosocial side effects that negatively impact quality of life. Although exercise is effective in mitigating these effects, adherence to traditional programs remains low. The Golf Recreational Exercise for Enhanced Survivorship (GREENS) program was developed as a novel multimodal recreational activity (MRA) integrating structured exercise with golf …

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