Archives: Research Papers

Associations between preoperative weight and body composition changes and surgical outcomes in patients with obesity and gastrointestinal cancer: a protocol for a prospective observational study in the active together cancer prehabilitation service.

INTRODUCTION: The impact of preoperative weight loss and body composition changes on surgical and patient-reported outcomes remains unclear in gastrointestinal cancer patients. Prehabilitation programmes integrating exercise, nutrition and psychological support can improve surgical readiness and recovery but the role of body mass and composition changes within such services is not well understood. This study aims to investigate the associations between …

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Practices, issues and possibilities at the interface between geriatrics and palliative care (InGaP): A case study exemplifying knotworking.

INTRODUCTION: With the recognition of the need for palliative care for people with non-malignant conditions, there is an increasing emphasis on interdisciplinary working between geriatric and palliative care teams. This interdisciplinary work has evolved organically; more needs to be known about current working practices. This is of policy and clinical interest as the older patient population continues to grow. METHODS: …

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Perceived exertion for guiding and monitoring exercise intensity in unsupervised, home-based cancer rehabilitation: an analysis of 3533 exercise sessions.

BACKGROUND: Exercise therapy is an essential part of cancer rehabilitation. Home-based, unsupervised exercise programs supported by digital tools offer a promising way to reduce access barriers. However, guiding and monitoring exercise intensity without supervision remains difficult. Rating of perceived exertion (RPE) is often used for this purpose, but its validity in unsupervised, home-based settings has not been systematically examined. In …

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Stress, inflammation, and resilience among patients with oral squamous cell carcinoma undergoing multimodal therapy: Current knowledge and future directions.

Oral squamous cell carcinoma represents a significant public health challenge in Asia, where multimodal therapies, while extending survival, impose substantial biologic and psychosocial stress. Sustained activation of the sympathetic-adrenal-medullary axis and dysregulation of the hypothalamic-pituitary-adrenal axis increase catecholamines, cortisol, interleukin-6, and C-reactive protein, accelerating tumor progression, impairing treatment tolerance, and increasing cardiovascular risk. Betel quid chewing, prevalent in the region, …

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A Scoping Review on Exercise Interventions During Adjuvant Chemotherapy or Radiotherapy for Cancer.

Cancer is one of the most common causes of death worldwide. Surgery, chemotherapy, and radiotherapy remain the first line of treatment for many different types of cancer. The diagnosis of cancer and its treatment lead to many physical and psychological symptoms. Several types of exercise interventions are available to help alleviate these symptoms. However, there is very little evidence available …

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Digital exercise interventions to improve physical functioning of people with breast cancer: Protocol for a scoping review.

INTRODUCTION: Breast cancer incidence rates are rising due to early detection, improved screening methods and advances in treatment options. As mortality rates reduce, there is a growing population living longer with treatment side-effects who require assistance. Prevalent issues arising after breast cancer treatment include pain, fatigue, lymphoedema and arm and shoulder mobility issues. Evidence demonstrates that upper limb exercises help …

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Physical Therapists in Oncology Settings: Experiences in Delivering Cancer Rehabilitation Services, Barriers to Care, and Service Development Needs.

OBJECTIVE: Physical therapist-delivered rehabilitation aims to manage the side effects of cancer and its treatments. Although access to cancer rehabilitation is not yet a standard of care in many countries, physical therapists practice in many types of cancer services with different cancer populations. The purpose of this study was to explore the experiences of physical therapists in cancer care practice …

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Morphofunctional Profile Focusing on Strength and Ultrasound of the Upper Limbs in Female Breast Cancer Survivors: A Comparative Cross-Sectional Study Between Groups with and Without Lymphoedema and Between Ipsilateral and Contralateral Limbs.

: Breast cancer is the most common neoplasm in women. Despite effective treatments, sequelae such as decreased muscle strength, upper limb dysfunction, and tissue changes are common, highlighting the need for functional assessments during rehabilitation. This study analysed the morphofunctional profile of the upper limbs in breast cancer survivors, comparing muscle strength and ultrasound findings between groups with and without …

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Prehabilitation in Adult Cancer Patients Undergoing Chemotherapy or Radiotherapy: A Scoping Review.

: The effectiveness and feasibility of cancer prehabilitation have been well-validated in surgical settings, but its role in non-surgical treatments, such as chemotherapy and radiotherapy (RT), remains unclear. This scoping review aims to systematically explore the existing literature on prehabilitation programs for non-surgical cancer treatments. : Following the scoping review methodology developed by the Joanna Briggs Institute, seven databases were …

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Development of a core screening, assessment and outcome set for cancer prehabilitation: an international Delphi consensus study protocol.

INTRODUCTION: A core screening, assessment and outcome set is needed in cancer prehabilitation to standardise what is measured in both research and services. Currently, there is significant variation in measures used, which limits comparability between studies and evidence synthesis. Standardising measures will improve the quality, comparability and impact of research by reducing heterogeneity between studies, minimising reporting bias, improving trial …

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