Archives: Research Papers

Molecular, cellular, biochemical, and rehabilitative insights into exercise interventions for gynecological cancer prevention and survivorship: a narrative review

Abstract This review paper investigated existing literature on the relationship between physical activity, exercise, and gynecological cancers, focusing on ovarian, endometrial, and cervical cancers. Epidemiological studies consistently demonstrate an inverse association between physical activity levels and the risk of developing gynecological cancers, as well as improved survival outcomes among cancer survivors engaging in regular exercise. Mechanistic insights suggest that physical …

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Implementation of electronic prospective surveillance models in cancer care: a scoping review

Abstract Background Electronic prospective surveillance models (ePSMs) for cancer rehabilitation include routine monitoring of the development of treatment toxicities and impairments via electronic patient-reported outcomes. Implementing ePSMs to address the knowledge-to-practice gap between the high incidence of impairments and low uptake of rehabilitation services is a top priority in cancer care. Methods We conducted a scoping review to understand the …

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Rehabilitation and physical activity during treatment of various types of cancer

Introduction and aim: Cancer is a health challenge for the entire human population. The number of oncological patients is increasing every year. Health challenges include not only prevention, diagnosis, treatment, but also rehabilitation. It is essential for patients to recover as much as possible. An analysis of numerous articles aims to demonstrate the validity of rehabilitation among oncology patients. Review …

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Socioeconomic position and employment status in patients with lung cancer – a register-based study

Background and purpose: Lung cancer patients have an increased risk of adverse employment outcomes. However, limited research exists on the association between socioeconomic position (SEP) and employment status in this cancer group. This study explored the influence of SEP on employment status after a lung cancer diagnosis. Patient/material and methods: This population-based cohort study included all working-age Danish residents diagnosed …

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Efficacy and safety of Xian-Lian-Jie-Du optimization decoction as an adjuvant treatment for prevention of recurrence in patients with stage IIIB/IIIC colon cancer: study protocol for a multicentre, randomized controlled trial

Abstract Introduction Colon cancer remains one of the most prevalent cancers worldwide. Unfortunately, there are no recognized and effective therapeutic strategies to prevent tumor recurrence after radical resection and chemotherapy, and the disease-free survival (DFS) in patients with stage IIIB or IIIC disease remains unsatisfactory. Xian-Lian-Jie-Du optimization decoction (XLJDOD) is a Chinese herbal medicine (CHM) empirical prescription, which has been …

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Localised Objective Characterisation Assessment of Lymphoedema (LOCAL): Using High-Frequency Ultrasound, Bioelectrical Impedance Spectroscopy and Volume to Evaluate Superficial Tissue Composition

Lymphoedema tissue is characterised by excess free fluid and structural changes to the extracellular matrix (ECM) in the form of fibrotic and fatty deposition. These tissue characteristics are integral to the assessment of lymphoedema progression; however, clinicians and researchers often focus on changes in the free fluid, volume and function of lymphatic vasculature to inform practice. Subsequently, little is known …

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Pitting Is Not Only a Measure of Oedema Presence: Using High-Frequency Ultrasound to Guide Pitting Test Standardisation for Assessment of Lymphoedema

The pitting qualities of lymphoedema tissue change with disease progression. However, little is known about the underlying tissue response to the pitting test or the tissue characteristics that enhance or resist indentation. The pitting test is currently unstandardised, and the influence of test technique on pitting outcomes is unknown. Understanding how tissue reacts to applied pressure will build evidence for …

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Development of an evidence-based educational resource in oncology: ‘Living safely with bone metastases’

Objective: To create an evidence-based patient education resource to better support cancer patients with bone metastases in carrying out safe movements during activities of daily living, to maintain their bone health and reduce the risk of fractures. Methods: A quality improvement project was conducted in three phases: Development of the Resource, Preliminary Feedback and Revision, and French Canadian Translation. Results: …

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Perspectives of Physiotherapists on Immune Functioning in Oncological Rehabilitation in the Netherlands: Insights from a Qualitative Study

Oncology physiotherapists frequently provide care for patients experiencing severe immunosuppression. Exercise immunology, the science that studies the effects of exercise on the immune system, is a rapidly evolving field with direct relevance to oncology physiotherapists. Understanding oncology physiotherapists’ perspectives on the subject of immune functioning is essential to explore its possible integration into clinical reasoning. This study aimed to assess …

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