Archives: Research Papers

Exercise-based interventions for postoperative rehabilitation in breast cancer patients: a systematic review and meta-analysis of randomized controlled trials

BACKGROUND: This systematic review and meta-analysis aim to evaluate the effects of exercise interventions on pain, lymphoedema, shoulder joint range of motion (ROM), muscle strength, and quality of life in postoperative breast cancer patients, and to provide evidence-based recommendations for clinical practice. METHODS: This systematic review and meta-analysis adhered to PRISMA guidelines and was registered on PROSPERO (CRD420251045309). A thorough …

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The role of virtual reality in breast cancer survivors: a scoping review [with consumer summary]

OBJECTIVE: This scoping review aims to analyze features, functions, and effectiveness evaluation of VR in the application of breast cancer care. METHODS: A scoping review was conducted based on the framework suggested by Arksey and O’Malley. Eight electronic databases (ie, PubMed, EMBASE, Cochrane Library, Web of Science, CINAHL, CNKI, China Wanfang Database, and China Biology Medicine disc.) was searched. Articles …

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Effectiveness of exercise-based interventions in preventing cancer therapy-related cardiac dysfunction in patients with breast cancer: a systematic review and network meta-analysis [with consumer summary]

BACKGROUND: Despite advances in cancer treatment that have improved survival rates among patients with breast cancer, they are at high risk of developing cancer therapy-related cardiac dysfunction, which typically manifests as heart failure. Although exercise improves cardiorespiratory fitness in these patients, its effectiveness in preventing cancer therapy-related cardiac dysfunction remains unclear. OBJECTIVE: To assess the effectiveness of exercise-based interventions using …

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2017 comprehensive update of the Canadian Cardiovascular Society guidelines for the management of heart failure (updated from 2006)

Since the inception of the Canadian Cardiovascular Society heart failure (HF) guidelines in 2006, much has changed in the care for patients with HF. Over the past decade, the HF Guidelines Committee has published regular updates. However, because of the major changes that have occurred, the Guidelines Committee believes that a comprehensive reassessment of the HF management recommendations is presently …

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Exploring prehabilitation interventions for patients with gynaecological cancer undergoing radiotherapy: a scoping review

PURPOSE: Radiotherapy imposes a significant physiological and psychological burden on gynaecological cancer patients. Prehabilitation is being increasingly used to prepare individuals for cancer treatment and improve their well-being and resilience. Whilst prehabilitation has demonstrated benefit for individuals undergoing cancer surgery, the structure, role and implementation of prehabilitation prior to radiotherapy are poorly defined and relatively unexplored. This scoping review aims …

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Effects of prehabilitation concurrent exercise on functional capacity in colorectal cancer patients: a systematic review and meta-analysis

PURPOSE: Our aim was to examine the efficacy of concurrent exercise (ie, aerobic and strength exercise) during prehabilitation programs on functional capacity in comparison with standard cancer care strategies in colorectal cancer (CRC) patients scheduled for surgery. METHODS: A systematic review of randomized controlled trials was performed. A search of electronic databases (PubMed, Web of Science, and EBSCO Host) was …

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Physical prehabilitation for older patients with cancer before complex medical-surgical interventions: an umbrella review

Prehabilitation has become a field of increasing interest over recent decades. However, few studies specifically investigated prehabilitation for older patients with cancer. The objective of this umbrella review was to summarize evidence on prehabilitation programs to identify the physical interventions that may be applied with benefit to older cancer patients who will undergo complex medical-surgical procedures. The protocol was registered …

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Presurgery exercise-based conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease (Cochrane review) [with consumer summary]

BACKGROUND: Lower limb peripheral arterial disease (PAD) is a type of cardiovascular disease where the blood vessels that carry the blood to the legs are hardened and narrowed. The most severe manifestation of PAD is critical limb ischaemia (CLI). This condition results in symptoms of intractable rest pain, non-healing wounds and ulceration, gangrene or both. PAD affects more than 200 …

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Prehabilitation versus no prehabilitation to improve functional capacity, reduce postoperative complications and improve quality of life in colorectal cancer surgery (Cochrane review) [with consumer summary]

BACKGROUND: Surgery is the cornerstone in curative treatment of colorectal cancer. Unfortunately, surgery itself can adversely affect patient health. ‘Enhanced Recovery After Surgery’ programmes, which include multimodal interventions, have improved patient outcomes substantially. However, these are mainly applied peri- and postoperatively. Multimodal prehabilitation includes multiple preoperative interventions to prepare patients for surgery with the aim of increasing resilience, thereby improving …

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Cardiovascular training versus resistance training for fatigue in people with cancer (Cochrane review) [with consumer summary]

BACKGROUND: With prevalence estimates between 50% and 90% of people with cancer, cancer-related fatigue is one of the most common morbidities related to cancer and its treatment. Exercise is beneficial for the treatment of cancer-related fatigue. However, the efficacy of different types of exercise (ie, cardiovascular training and resistance training) have not yet been investigated systematically and compared directly in …

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