Research Topic: Humans

Feasibility of High-Intensity Interval Exercise in Young Adult Survivors of Pediatric Brain Tumor and Young Adults With Isocitrate Dehydrogenase-Mutant Gliomas (HYPE): Protocol for a Randomized Controlled Trial.

BACKGROUND: Young adult survivors of pediatric brain tumors and young adult patients with isocitrate dehydrogenase (IDH) mutant gliomas are at risk for cognitive impairment, reduced physical fitness and function, as well as poor health-related quality of life (HRQOL) and psychosocial health. Exercise improves these outcomes; however, both populations remain understudied with respect to exercise interventions. High-intensity interval training (HIIT) is …

Read more

Chemotherapy-Induced Skeletal Muscle Dysfunction and Cognitive Impairment: A Muscle-Brain Mechanistic Framework With Implications for Exercise Oncology.

Chemotherapy commonly induces skeletal muscle dysfunction and cognitive impairment, complications that reduce treatment tolerance and quality of life. Skeletal muscle mass frequently declines during chemotherapy, with cohort studies reporting losses of 3%-10% across treatment courses, while chemotherapy-induced cognitive impairment affects up to one-third of patients. Emerging evidence indicates that chemotherapeutic agents impair mitochondrial function in peripheral tissues, including skeletal muscle, …

Read more

Therapeutic Exercise Protocol During Hospitalization in Pediatric Oncohematological Patients: Randomized Clinical Trial.

BACKGROUND: Leukemias, lymphomas, and central nervous system tumors are among the most common pediatric cancers and may lead to motor deficits, impaired balance, reduced muscle strength, fatigue, and decreased functional capacity. Early physiotherapy during hospitalization may help prevent inactivity and support functional preservation in this population. OBJECTIVE: To evaluate the effects of a therapeutic exercise program on quality of life, …

Read more

Association Between Danish Guideline Treatments for Breast Cancer and Physiotherapy-Relevant Late Effects: A Nationwide Cohort Study.

BACKGROUND: Breast cancer survival has improved substantially, yet many women continue to experience late effects that may require physiotherapy. Shoulder impairment, lymphedema, and fatigue are among the most common physiotherapy-relevant late effects following primary breast cancer treatment. Understanding how guideline treatments for breast cancer influence these impairments is essential for the early identification of high-risk patients and the development of …

Read more

Cost-effectiveness of a web-based peer-delivered physical activity program for breast cancer survivors.

BACKGROUND: Breast cancer survivors are increasing in number and living longer but often experience reduced quality of life (QOL) from treatment sequelae. Physical activity (PA) interventions can improve QOL, but many rely on costly specialists or are difficult to scale. We adapted an evidence-based peer-mentoring program (moving forward together) for web delivery (webMFT). The platform centralizes peer-coach matching, delivery, and …

Read more

Effects of Exercise-Based Interventions on Depressive Symptoms in Adults with Lung Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

: Exercise is increasingly used in supportive care for lung cancer, but its effects on depressive symptoms remain uncertain. This systematic review and meta-analysis synthesized randomized evidence. : Four electronic databases were searched for reports published from January 2000 to July 2026. Eligible studies enrolled adults with lung cancer and compared a structured exercise-based intervention with usual care or an …

Read more

Exploring the feasibility of exercise training during (neo)adjuvant chemotherapy in women with early-stage breast cancer: a pilot study examining immune and metabolic outcomes.

PURPOSE: To examine the feasibility and exploratory immunological, metabolic, and patient-reported effects of a supervised exercise intervention during (neo)adjuvant chemotherapy in women with early-stage breast cancer. METHODS: This non-randomised pilot study examined a 12-week supervised combined aerobic and resistance exercise programme during (neo)adjuvant treatment. Participants self-selected into the exercise intervention, and as no eligible participants opted for the control group, …

Read more

Exercise and Childhood Cancer: From Science to Life “The 3rd Pediatric Exercise Oncology Congress Meets FORTEe”.

On behalf of the organizing committee, we are pleased to present the abstracts from the 2026 conference, “PEOC meets FORTEe”. The Third Pediatric Exercise Oncology Congress, this year meeting in person with the EU Study FORTEe (Get Strong to Fight Childhood Cancer: An Exercise Intervention for Children and Adolescents Undergoing Anti-Cancer Treatment), brought together scientists, clinicians, exercise professionals, physiotherapists, patients, …

Read more

Patient Perspectives on Prostate Cancer Prehabilitation: A Qualitative Study Using the Behaviour Change Wheel to Investigate Barriers and Facilitators to Engagement.

Cancer prehabilitation aims to improve outcomes by helping patients physically and mentally prepare for treatment. This qualitative study aimed to investigate barriers and facilitators to engaging in prostate cancer prehabilitation and create recommendations for designing interventions. Semi-structured interviews were used to explore perspectives on cancer prehabilitation among men diagnosed with prostate cancer in Alberta, Canada. Interviews were thematically analyzed to …

Read more

A multidisciplinary intervention to support return to work of individuals with breast cancer: a prospective feasibility study.

PURPOSE: Work participation is one of the aims of cancer rehabilitation for individuals with breast cancer (BC). This study aimed to verify the feasibility of a multidisciplinary intervention addressing the work-related difficulties of working-age individuals with BC. METHODS: In this prospective feasibility study, employed individuals with BC who reported work-related difficulties were eligible. Participants were assessed at baseline (T0), 1 …

Read more

© 2026 OncoPhysio.com
About me Contact
Disclaimer & Privacy Policy Payment Policy