Research Topic: Female

Therapeutic Exercise Protocol During Hospitalization in Pediatric Oncohematological Patients: Randomized Clinical Trial.

BACKGROUND: Leukemias, lymphomas, and central nervous system tumors are among the most common pediatric cancers and may lead to motor deficits, impaired balance, reduced muscle strength, fatigue, and decreased functional capacity. Early physiotherapy during hospitalization may help prevent inactivity and support functional preservation in this population. OBJECTIVE: To evaluate the effects of a therapeutic exercise program on quality of life, …

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Association Between Danish Guideline Treatments for Breast Cancer and Physiotherapy-Relevant Late Effects: A Nationwide Cohort Study.

BACKGROUND: Breast cancer survival has improved substantially, yet many women continue to experience late effects that may require physiotherapy. Shoulder impairment, lymphedema, and fatigue are among the most common physiotherapy-relevant late effects following primary breast cancer treatment. Understanding how guideline treatments for breast cancer influence these impairments is essential for the early identification of high-risk patients and the development of …

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Cost-effectiveness of a web-based peer-delivered physical activity program for breast cancer survivors.

BACKGROUND: Breast cancer survivors are increasing in number and living longer but often experience reduced quality of life (QOL) from treatment sequelae. Physical activity (PA) interventions can improve QOL, but many rely on costly specialists or are difficult to scale. We adapted an evidence-based peer-mentoring program (moving forward together) for web delivery (webMFT). The platform centralizes peer-coach matching, delivery, and …

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Exploring the feasibility of exercise training during (neo)adjuvant chemotherapy in women with early-stage breast cancer: a pilot study examining immune and metabolic outcomes.

PURPOSE: To examine the feasibility and exploratory immunological, metabolic, and patient-reported effects of a supervised exercise intervention during (neo)adjuvant chemotherapy in women with early-stage breast cancer. METHODS: This non-randomised pilot study examined a 12-week supervised combined aerobic and resistance exercise programme during (neo)adjuvant treatment. Participants self-selected into the exercise intervention, and as no eligible participants opted for the control group, …

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A multidisciplinary intervention to support return to work of individuals with breast cancer: a prospective feasibility study.

PURPOSE: Work participation is one of the aims of cancer rehabilitation for individuals with breast cancer (BC). This study aimed to verify the feasibility of a multidisciplinary intervention addressing the work-related difficulties of working-age individuals with BC. METHODS: In this prospective feasibility study, employed individuals with BC who reported work-related difficulties were eligible. Participants were assessed at baseline (T0), 1 …

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Identification of high-impact chronic pain among cancer survivors: a cross-sectional study using the Graded Chronic Pain Scale framework.

PURPOSE: Chronic cancer-related pain is a prevalent and often under-recognized issue among individuals living with or after cancer. Clinically useful tools are needed to classify pain severity and impact and to identify those requiring targeted support. This study applied the Graded Chronic Pain Scale-Revised (GCPS-R) in a cohort of cancer survivors and examined differences in pain characteristics and psychosocial factors …

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Psychological Readiness for Surgery Through Prehabilitation and Treatment: A Longitudinal Qualitative Study.

BACKGROUND: Psychological prehabilitation aims to prepare patients for cancer treatment, yet psychological readiness is under-specified and distress during and after treatment is common. A patient-informed account of readiness is needed to guide readiness-focused, proactive psychological support in cancer care. AIMS: To examine patients’ experiences of psychological readiness for cancer surgery across the prehabilitation-treatment pathway. METHODS: We used a longitudinal qualitative …

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Long-term prospective assessment of quality of life and physical function in malignant lymphoma patients undergoing chemotherapy.

This study aims to evaluate longitudinal changes in health state utility values, health-related quality of life, physical function, nutritional status, and fatigue in patients with malignant lymphoma from the start of chemotherapy to 1 year post-chemotherapy and clarify the implications for survivorship care planning. This prospective observational study included 21 patients hospitalized for chemotherapy who also received exercise therapy. Assessments …

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Graded Exercise Therapy and Cognitive Behavioral Therapy for Fatigue in Patients With Breast Cancer: Protocol for a Randomized Controlled Pilot Study.

BACKGROUND: Fatigue is a common debilitating symptom of breast cancer (BC), and its treatment may result in a significant symptom burden and affect adherence to treatment. Graded exercise therapy (GET) and cognitive behavioral therapy (CBT) have separately been shown in previous studies to be beneficial for the management of cancer-related fatigue. OBJECTIVE: This study’s coprimary aims are to assess the …

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Effects of exercise therapy on chemotherapy delivery and response in primary breast cancer: A secondary analysis of a randomized trial.

BACKGROUND: Whether structured exercise therapy improves chemotherapy delivery, tolerability, and tumor response is unclear. METHODS: This was a secondary analysis of a phase 2 trial investigating exercise therapy (n = 72) versus usual care (n = 72) in patients with primary breast cancer. Exercise therapy comprised individualized treadmill walking three times weekly for 20-50 minutes per session at 55%-100% of pretreatment exercise capacity. Chemotherapy …

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