Research Topic: Female

Dynamic task-based rehabilitation and time to loss of toilet ambulation in a palliative care unit: a retrospective cohort study.

PURPOSE: To determine whether dynamic-task rehabilitation, compared with bedside-only or no rehabilitation, is associated with longer time to loss of toilet ambulation among patients with advanced cancer in a palliative care unit (PCU). METHODS: This retrospective study included patients with cancer admitted to a PCU who died during hospitalization (January 2020-March 2024). Eligible patients had walked to an in-room fixed …

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Exploring optimal group dynamics and their feasibility during a live-remote exercise program for cancer survivors: an international concept mapping study.

PURPOSE: Live-remote supervised exercise helps cancer survivors reduce the negative side effects of their treatment, and group dynamics are an integral aspect of successful rehabilitation outcomes. In this international group concept mapping study, we investigated which aspects of peer interaction and trainer behaviour participants consider important and how feasible those preferences are according to exercise professionals. METHODS: Participants who completed …

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Associations of Cancer Rehabilitation During Hospitalization for Cancer Treatment With Survival and Post-Discharge Healthcare Utilization: A Multicenter Retrospective Cohort Study.

BACKGROUND: Rehabilitation is increasingly recognized as an essential component of oncology care, but there remains limited evidence regarding its broader impact on patient outcomes. This study examined the associations of inpatient cancer rehabilitation with survival and post-discharge healthcare utilization among patients with diverse cancer types. METHODS: We conducted a multicenter retrospective cohort study using cancer registry-linked claims data from designated …

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A Remotely Delivered Exercise-Based Rehabilitation Program for Patients with Persistent Chemotherapy-Induced Peripheral Neuropathy (EX-CIPN): A Phase I Feasibility Trial.

BACKGROUND: Chemotherapy-induced peripheral neuropathy (CIPN) affects two-thirds of patients who receive neurotoxic chemotherapy. In almost half of these patients, CIPN is persistent, with limited treatment options. Exercise-based rehabilitation shows promising results in improving CIPN-related outcomes, but high-quality research is needed with CIPN symptoms and disability as primary endpoints. METHODS: We conducted a phase I single-arm, multi-method pilot study of a …

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Therapeutic Exercise Protocol During Hospitalization in Pediatric Oncohematological Patients: Randomized Clinical Trial.

BACKGROUND: Leukemias, lymphomas, and central nervous system tumors are among the most common pediatric cancers and may lead to motor deficits, impaired balance, reduced muscle strength, fatigue, and decreased functional capacity. Early physiotherapy during hospitalization may help prevent inactivity and support functional preservation in this population. OBJECTIVE: To evaluate the effects of a therapeutic exercise program on quality of life, …

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Association Between Danish Guideline Treatments for Breast Cancer and Physiotherapy-Relevant Late Effects: A Nationwide Cohort Study.

BACKGROUND: Breast cancer survival has improved substantially, yet many women continue to experience late effects that may require physiotherapy. Shoulder impairment, lymphedema, and fatigue are among the most common physiotherapy-relevant late effects following primary breast cancer treatment. Understanding how guideline treatments for breast cancer influence these impairments is essential for the early identification of high-risk patients and the development of …

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Cost-effectiveness of a web-based peer-delivered physical activity program for breast cancer survivors.

BACKGROUND: Breast cancer survivors are increasing in number and living longer but often experience reduced quality of life (QOL) from treatment sequelae. Physical activity (PA) interventions can improve QOL, but many rely on costly specialists or are difficult to scale. We adapted an evidence-based peer-mentoring program (moving forward together) for web delivery (webMFT). The platform centralizes peer-coach matching, delivery, and …

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Exploring the feasibility of exercise training during (neo)adjuvant chemotherapy in women with early-stage breast cancer: a pilot study examining immune and metabolic outcomes.

PURPOSE: To examine the feasibility and exploratory immunological, metabolic, and patient-reported effects of a supervised exercise intervention during (neo)adjuvant chemotherapy in women with early-stage breast cancer. METHODS: This non-randomised pilot study examined a 12-week supervised combined aerobic and resistance exercise programme during (neo)adjuvant treatment. Participants self-selected into the exercise intervention, and as no eligible participants opted for the control group, …

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A multidisciplinary intervention to support return to work of individuals with breast cancer: a prospective feasibility study.

PURPOSE: Work participation is one of the aims of cancer rehabilitation for individuals with breast cancer (BC). This study aimed to verify the feasibility of a multidisciplinary intervention addressing the work-related difficulties of working-age individuals with BC. METHODS: In this prospective feasibility study, employed individuals with BC who reported work-related difficulties were eligible. Participants were assessed at baseline (T0), 1 …

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Identification of high-impact chronic pain among cancer survivors: a cross-sectional study using the Graded Chronic Pain Scale framework.

PURPOSE: Chronic cancer-related pain is a prevalent and often under-recognized issue among individuals living with or after cancer. Clinically useful tools are needed to classify pain severity and impact and to identify those requiring targeted support. This study applied the Graded Chronic Pain Scale-Revised (GCPS-R) in a cohort of cancer survivors and examined differences in pain characteristics and psychosocial factors …

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